JA2131

• Catalog Number: orb1744135
• Category: Small Molecules
• Description: JA2131
• CAS Number: 6505-99-3
• MW: 341.45
• SMILES: S=C1C2=C(N=C(SCCN3CCOCC3)N2)N(C)C(=O)N1C
• Formula: C₁₃H₁₉N₅O₂S₂
• Biological Activity: JA2131 is a small molecular inhibitor targeting Poly(ADP-ribose) Glycohydrolase (PARG) with an IC50 value of 0.4 μM. It modulates DNA damage responses, induces replication fork stalling, and leads to cancer cell death.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.