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Catalog Number | orb1299039 |
---|---|
Category | Small Molecules |
Description | J14 |
CAS Number | 1043854-13-2 |
Purity | 96.93% |
MW | 517.04 |
SMILES | S(CC1=CC=C(C(O)=O)C=C1)C=2N=C(C=C(N2)C3=CC=CC=C3)N4CCN(CC4)C5=C(Cl)C=CC=C5 |
Formula | C28H25ClN4O2S |
Biological Activity | J-14 is an inhibitor of reversible sulfiredoxin(IC50 : 8.1 μM). J14 induces oxidative stress (intracellular ROS accumulation) by inhibiting sulfiredoxin, leading to cytotoxicity and cancer cell death |
Storage | Store at -20°C for 12 months. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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