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Catalog Number | orb1300396 |
---|---|
Category | Small Molecules |
Description | Ixabepilone |
CAS Number | 219989-84-1 |
Purity | 98.60% |
MW | 506.7 |
SMILES | C[C@@]12[C@@](O1)(C[C@@H](\C(=C\C=3N=C(C)SC3)\C)NC(=O)C[C@H](O)C(C)(C)C(=O)[C@H](C)[C@@H](O)[C@@H](C)CCC2)[H] |
Formula | C27H42N2O5S |
Biological Activity | Ixabepilone (Azaepothilone B) is an orally bioavailable microtubule inhibitor. It binds to tubulin and promotes tubulin polymerization and microtubule stabilization, thereby arresting cells in the G2-M phase of the cell cycle and inducing tumor cell apoptosis. |
Storage | Store at -20°C for 12 months. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
> 98% (HPLC) | |
219989-84-1 |
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