IWR-1

• Catalog Number: orb180916
• Category: Small Molecules
• Description: IWR-1 (endo-IWR 1) is a Wnt pathway inhibitor with IC50 of 180 nM, induces Axin2 protein levels and promotes β-catenin phosphorylation by stabilizing Axin-scaffolded destruction complexes.
• CAS Number: [1127442-82-3]
• MW: 409.4367
• SMILES: O=C1C2([H])C3([H])C([H])=C([H])C([H])(C3([H])[H])C2([H])C(N1C1C([H])=C([H])C(C(N([H])C2=C([H])C([H])=C([H])C3C([H])=C([H])C([H])=NC2=3)=O)=C([H])C=1[H])=O
• Formula: C₂₅H₁₉N₃O₃
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

Chemical structure of IWR-1