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Catalog Number | orb1301871 |
---|---|
Category | Small Molecules |
Description | IWP-O1 |
CAS Number | 2074607-48-8 |
Purity | 99.98% |
MW | 432.48 |
SMILES | C(C(NC1=CC=C(C=N1)C2=CC=CC=C2)=O)N3C(=C(N=N3)C=4C=CN=CC4)C5=CC=CC=C5 |
Formula | C26H20N6O |
Biological Activity | IWP-O1 is a highly potent Porcupine (Porcn) inhibitor (EC50: 80 pM), effectively suppresses the phosphorylation of Dvl2/3 and LRP6 in HeLa cells. |
Storage | Store at -20°C for 12 months. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
> 98% (HPLC) | |
2074607-48-8 |
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