Itacitinib (INCB039110)

• Catalog Number: orb573019
• Category: Small Molecules
• Description: Itacitinib is a potent and selective inhibitor of JAK1, with > 20-fold selectivity for JAK1 over JAK2 and > 100-fold over JAK3 and TYK2; Itacitinib is used in the research of myelofibrosis.
• CAS Number: [1334298-90-6]
• MW: 553.5141
• SMILES: FC1C(C(F)(F)F)=NC([H])=C([H])C=1C(N1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])N1C([H])([H])C(C([H])([H])C#N)(C1([H])[H])N1C([H])=C(C2=C3C([H])=C([H])N([H])C3=NC([H])=N2)C([H])=N1)=O
• Formula: C₂₆H₂₃F₄N₉O
• Note: For research use only
• Expiration Date: 12 months from date of receipt.