Israpafant

• Catalog Number: orb1700317
• Category: Small Molecules
• Description: Israpafant
• CAS Number: 117279-73-9
• Purity: 98%
• MW: 489.07
• SMILES: CC=1N2C3=C(C(=NC(C)C2=NN1)C4=C(Cl)C=CC=C4)C=C(CCC5=CC=C(CC(C)C)C=C5)S3
• Formula: C₂₈H₂₉ClN₄S
• Biological Activity: Israpafant is a selective antagonist for the platelet-activating factor receptor ( IC50 = 0.84nM). Israpafant inhibits PAF-induced human platelet aggregation. Israpafant inhibits the activation of eosinophil cells and consequently delays the development of immune responses. Israpafant also has anti-nephrotoxic properties and to mobilize calcium transport.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.