Isosilybin A

• Catalog Number: orb1297319
• Category: Small Molecules
• Description: Isosilybin A
• CAS Number: 142796-21-2
• Purity: 98%
• MW: 482.44
• SMILES: COc1cc(ccc1O)[C@H]1Oc2ccc(cc2O[C@@H]1CO)[C@H]1Oc2cc(O)cc(O)c2C(=O)[C@@H]1O
• Formula: C₂₅H₂₂O₁₀
• Biological Activity: Isosilybin A is a partial PPARγ agonist, it significantly induced ABCA1 protein expression, it inhibited both monophenolase (IC50=1.7-7.6μM) and diphenolase (IC50=12.1-44.9μM) of tyrosinase. Isosilybin A shows anti-angiogenic efficacy, it has anti-prostate cancer (PCA) activity that is mediated via cell cycle arrest and apoptosis induction.
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.