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Isoguanosine-5'-O-triphosphate sodium

Isoguanosine-5'-O-triphosphate sodium

Catalog Number: orb2276818

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Catalog Numberorb2276818
CategorySmall Molecules
DescriptionIsoguanosine-5'-O-triphosphate, an isomer of guanosine 5'-triphosphate (GTP) and a phosphorylated derivative of crotonoside, does not promote microtubule assembly like GTP. At a concentration of 2 mM, it hampers transcription and triggers T to C mutations in reverse transcriptase assays. This compound aids in assessing the substrate specificity of both phosphofructokinase and mutT homolog 1 (MTH1).
Purity98.00%
MW611.11
SMILESO[C@@H]1[C@H](O)[C@@H](COP([O-])(OP(OP([O-])([O-])=O)([O-])=O)=O)O[C@H]1N2C=NC(C(N)=N3)=C2NC3=O.[Na+].[Na+].[Na+].[Na+]
FormulaC10H12N5O14P3.4Na
Biological ActivityIsoguanosine-5'-O-triphosphate, an isomer of guanosine 5'-triphosphate (GTP) and a phosphorylated derivative of crotonoside, does not promote microtubule assembly like GTP. At a concentration of 2 mM, it hampers transcription and triggers T to C mutations in reverse transcriptase assays. This compound aids in assessing the substrate specificity of both phosphofructokinase and mutT homolog 1 (MTH1).
Storage-20°C
NoteFor research use only
Expiration Date12 months from date of receipt.