Ipatasertib-NH2

• Catalog Number: orb1988275
• Category: Small Molecules
• Description: Ipatasertib-NH2 (GDC-0068-NH2;RG7440-NH2) is a ligand for the target protein AKT used in PROTAC, binding to lenalidomide, a ligand of ubiquitin E3 ligase cereblon (CRBN), via a ten-hydrocarbon linker to form INY-03-041 for AKT degradation[1].
• CAS Number: 1001382-14-4
• Purity: 98.00%
• MW: 415.92
• SMILES: C[C@H]1C2=C(N=CN=C2[C@H](O)C1)N3CCN(C([C@H](CN)C4=CC=C(Cl)C=C4)=O)CC3
• Formula: C₂₁H₂₆ClN₅O₂
• Biological Activity: Ipatasertib-NH2 (GDC-0068-NH2;RG7440-NH2) is a ligand for target protein AKT for PROTAC, binds to lenalidomide, a ligand of ubiquitin E3 ligase cereblon (CRBN), via a ten-hydrocarbon linker to form INY-03-041 to degrade AKT[1].
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.