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Catalog Number | orb1983287 |
---|---|
Category | Small Molecules |
Description | INY-03-041 trihydrochloride, a potent and highly selective PROTAC-based pan-AKT degrader, comprises Ipatasertib, an ATP-competitive AKT inhibitor, conjugated to Lenalidomide. It effectively inhibits AKT1, AKT2, and AKT3 with IC50 values of 2.0, 6.8, and 3.5 nM, respectively [1]. |
Purity | 98.00% |
MW | 907.8 |
Formula | C44H59Cl4N7O5 |
Biological Activity | INY-03-041 trihydrochloride, a potent and highly selective PROTAC-based pan-AKT degrader, comprises Ipatasertib, an ATP-competitive AKT inhibitor, conjugated to Lenalidomide. It effectively inhibits AKT1, AKT2, and AKT3 with IC50 values of 2.0, 6.8, and 3.5 nM, respectively [1]. |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |