You have no items in your shopping cart.
You have no items in your shopping cart.
Catalog Number | orb1954183 |
---|---|
Category | Proteins |
Description | Integrin alpha-V & beta-3 (ITGAV/ITGB3) is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. |
Tag | C-His |
Purity | SDS-PAGE: 94.9%; SEC-HPLC: 91.6% |
MW | 193.32 kDa (predicted) |
UniProt ID | P05106, P06756 |
Expression System | HEK293 Cells |
Biological Origin | Human |
Biological Activity | Integrin alpha-V & beta-3 (ITGAV/ITGB3) is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. |
Expression Region | A DNA sequence encoding the extracellular domain (Met1-Val992) of human ITGAV (P06756) was fused with a his tag at the C-terminus, constructed the plasmid 1; A DNA sequence encoding the extracellular domain (Met1-Asp718) of human ITGB3 (P05106) constructed the plasmid 2. The two plasmids were co-expressed and the human ITGAV&ITGB3 heterodimer was purified. Predicted N terminal: Phe31 & Gly27 |
Storage | -20°C |
Note | For research use only |
Application notes | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
Expiration Date | 6 months from date of receipt. |
> 95% as determined by Tris-Bis PAGE; > 95% as determined by SEC-HPLC | |
Due to glycosylation,the protein migrates to 85-140 kDa based on Tris-Bis PAGE result. |
> 95% as determined by Tris-Bis PAGE; > 95% as determined by SEC-HPLC | |
Due to glycosylation,the protein migrates to 85-140 kDa based on Tris-Bis PAGE result. |
> 90% as determined by SDS-PAGE | |
31.5 kDa |
> 95% by Tris-Bis PAGE, > 95% by SEC-HPLC | |
Recombinant Human Integrin ITGAV & ITGB3 Protein is produced by Expi293 expression system. The target protein is expressed with sequence (Phe31-Val992(P06756) acidic tail&GLy27-Asp718(P05106) basic tail) of Human Integrin ITGAV & ITGB3 fused with His Tag and Avi tag at the C-terminal. |