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Catalog Number | orb1992826 |
---|---|
Category | Small Molecules |
Description | Imatinib-d8 (STI571 D8) is a 2H-labeled version of Imatinib. Imatinib is a multi-target receptor tyrosine kinase inhibitor with anti-tumor activity, selectively inhibiting BCR-ABL, v-Abl, PDGFR, c-kit kinases, and is used in chronic myeloid leukemia treatment. |
CAS Number | 1092942-82-9 |
Purity | 98.00% |
MW | 501.65 |
SMILES | N(C=1N=C(C=CN1)C=2C=CC=NC2)C3=CC(NC(=O)C4=CC=C(CN5C(C(N(C)C(C5([2H])[2H])([2H])[2H])([2H])[2H])([2H])[2H])C=C4)=CC=C3C |
Formula | C29H23D8N7O |
Biological Activity | Imatinib D8 is a deuterium-labeled Imatinib. Imatinib is an orally bioavailable tyrosine kinases inhibitor that inhibits BCR/ABL, PDGFR, v-Abl, and c-kit kinase activity. |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |