You have no items in your shopping cart.
Cart summary
IL-18BP Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated
Catalog Number: orb1960404
| Catalog Number | orb1960404 |
|---|---|
| Category | Proteins |
| Description | Cytokines were the first modern immunotherapies to produce durable responses in patients with advanced cancer,components of the interleukin-18 (IL-18) pathway are upregulated on tumour-infiltrating lymphocytes, suggesting that IL-18 therapy could enhance anti-tumour immunity. IL-18BP, a high-affinity IL-18 decoy receptor, is frequently upregulated in diverse human and mouse tumours and limits the anti-tumour activity of IL-18 in mice. IL-18BP Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 21.14 kDa and the accession number is A0A2K5UDJ4. |
| Tag | C-His |
| Purity | 98.00% |
| MW | 21.14 kDa (predicted). Due to glycosylation, the protein migrates to 50-65 kDa based on Tris-Bis PAGE result. |
| UniProt ID | A0A2K5UDJ4 |
| Expression System | HEK293 Cells |
| Biological Origin | Cynomolgus |
| Biological Activity | Cytokines were the first modern immunotherapies to produce durable responses in patients with advanced cancer,components of the interleukin-18 (IL-18) pathway are upregulated on tumour-infiltrating lymphocytes, suggesting that IL-18 therapy could enhance anti-tumour immunity. IL-18BP, a high-affinity IL-18 decoy receptor, is frequently upregulated in diverse human and mouse tumours and limits the anti-tumour activity of IL-18 in mice. IL-18BP Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 21.14 kDa and the accession number is A0A2K5UDJ4. |
| Expression Region | Thr28-Pro207 |
| Storage | -20°C |
| Note | For research use only |
| Expiration Date | 6 months from date of receipt. |
