IL-15 mutant Recombinant Protein (biotin)

• Catalog Number: orb1229913
• Category: Proteins
• Description: IL-15 mutant Recombinant Protein (biotin)
• Tag: Fc Tag
• Dilution range: This recombinant proteins is for research use only.
• Form/Appearance: Lyophilized
• Purity: > 98% (SDS-PAGE). Endotoxin level is less than 0.06EU/ μg protein (LAL test; Lonza).
• Target: IL15
• UniProt ID: O88516
• Protein Sequence: The extracellular domain of human IL-15 (aa 49-162) including mutations at Q149D and Q156D is fused to the N-terminus of the Fc region of mouse IgG2a.
• Source: CHO cells
• Biological Activity: This mutant IL-15/Fc fusion protein specifically binds to the IL-15R, competitively inhibits IL-15-triggered cell proliferation, promotes transplant tolerance, does not activate the STAT-signaling pathway, and exerts a prolonged circulating half-life caused by the modified Fc domain.
• NCBI: NP_751914
• Storage: Stable for at least 6 months after receipt when stored at +4°C.
• Buffer/Preservatives: In PBS and 0.09% sodium azide.
• Alternative names: Interleukin-15
• Note: For research use only
• Application notes: This recombinant proteins is for research use only.
• Expiration Date: 6 months from date of receipt.