IL-1 alpha/IL-1A Protein, Cynomolgus, Recombinant (His)

• Catalog Number: orb1959996
• Category: Proteins
• Description: The interleukin (IL)-1 family of cytokines is currently comprised of 11 members that have pleiotropic functions in inflammation and cancer. IL-1α and IL-1β were the first members of the IL-1 family to be described, and both signal via the same receptor, IL-1R. Over the last decade, much progress has been made in our understanding of biogenesis of IL-1β and its functions in human diseases.
• Tag: C-His
• Purity: 98.00%
• MW: 19.23 kDa (predicted). Due to glycosylation, the protein migrates to 25-35 kDa based on Tris-Bis PAGE result.
• UniProt ID: P79340
• Expression System: HEK293 Cells
• Biological Origin: Cynomolgus
• Biological Activity: The interleukin (IL)-1 family of cytokines is currently comprised of 11 members that have pleiotropic functions in inflammation and cancer. IL-1α and IL-1β were the first members of the IL-1 family to be described, and both signal via the same receptor, IL-1R. Over the last decade, much progress has been made in our understanding of biogenesis of IL-1β and its functions in human diseases.
• Expression Region: Ser113-Ala271
• Storage: -20°C
• Note: For research use only
• Application notes: Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
• Expiration Date: 6 months from date of receipt.