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IHMT-PI3K-455
Catalog Number: orb2278369
| Catalog Number | orb2278369 |
|---|---|
| Category | Small Molecules |
| Description | IHMT-PI3K-455 (Compound 15u) is a potent, selective PI3Kγ/δ dual inhibitor with IC50 values of 7.1 nM for PI3Kγ and 0.57 nM for PI3Kδ, exhibiting oral activity. This compound inhibits AKT phosphorylation and promotes tumor regression by recruiting and activating CD8+ T cells. It is utilized in cancer research [1]. |
| Purity | 98.00% |
| MW | 517.49 |
| Formula | C26H21F2N7O3 |
| Biological Activity | IHMT-PI3K-455 (Compound 15u) is a potent, selective PI3Kγ/δ dual inhibitor, demonstrating oral activity, with IC50 values of 7.1 nM for PI3Kγ and 0.57 nM for PI3Kδ. This compound inhibits AKT phosphorylation and promotes tumor regression through the recruitment and activation of CD8+ T cells. It is utilized in cancer research [1]. |
| Storage | -20°C |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
