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Catalog Number | orb750208 |
---|---|
Category | Antibodies |
Description | This antibody is specific to Insulin-like Growth Factor (IGF1) and shows minimal cross-reaction with IGF-11, Proinsulin, MSF, and Insulin. IGF1 is a polypeptide growth factor with two isoforms that are produced by alternative splicing. Isoform 1 is also known as IGF-IB while isoform 2 is known as IGF-IA. IGF1 stimulates the proliferation of a wide range of cell types including muscle, bone and cartilage tissue. It functions as an autocrine regulator of growth. Activation of IGF system has emerged as a key factor for tumor progression and resistance to apoptosis in many cancers like those of breast, thyroid and colon. |
Species/Host | Mouse |
Clonality | Monoclonal |
Clone Number | SPM406 |
Tested applications | IHC-P |
Reactivity | Human |
Isotype | Mouse IgG1, kappa |
Immunogen | Purified human IGF1 protein was used as the immunogen for this IGF-1 antibody. |
Dilution range | Immunohistochemistry (FFPE): 1-2ug/ml (1) |
Purity | Protein G affinity chromatography |
Conjugation | Unconjugated |
Formula | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide |
Hazard Information | This IGF-1 antibody is available for research use only. |
UniProt ID | P05019 |
Storage | Store the IGF-1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide). |
Buffer/Preservatives | 0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin (US sourced) and 0.05% sodium azide |
Note | For research use only |
Application notes | Optimal dilution of the antibody should be determined by the researcher. |
Expiration Date | 12 months from date of receipt. |
FACS | |
Human, Mouse, Rat | |
Rabbit | |
Recombinant | |
Unconjugated |
FACS, IF, NeA | |
Human, Mouse, Rat | |
Mouse | |
Monoclonal | |
Unconjugated |
FACS, IF, NeA | |
Human, Mouse, Rat | |
Mouse | |
Monoclonal | |
Unconjugated |
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