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Catalog Number | orb639893 |
---|---|
Category | Antibodies |
Description | This antibody is specific to Insulin-like Growth Factor (IGF-1) and shows minimal cross-reaction with IGF-11, Proinsulin, MSF, and Insulin. IGF-1 is a polypeptide growth factor with two isoforms that are produced by alternative splicing. Isoform 1 is also known as IGF-IB while isoform 2 is known as IGF-IA. IGF-1 stimulates the proliferation of a wide range of cell types including muscle, bone and cartilage tissue. It functions as an autocrine regulator of growth. Activation of IGF system has emerged as a key factor for tumor progression and resistance to apoptosis in many cancers like those of breast, thyroid and colon. |
Species/Host | Rabbit |
Clonality | Recombinant |
Clone Number | IGF1/2872R |
Tested applications | FACS |
Reactivity | Human, Mouse, Rat |
Isotype | Rabbit IgG |
Immunogen | Recombinant full-length human protein was used as the immunogen for the recombinant Insulin-like Growth Factor 1 antibody. |
Dilution range | Flow cytometry: 1-2ug/million cells in 0.1ml |
Purity | Protein A affinity chromatography |
Conjugation | Unconjugated |
Formula | 0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide |
Hazard Information | This recombinant Insulin-like Growth Factor 1 antibody is available for research use only. |
UniProt ID | P05019 |
Storage | Store the recombinant Insulin-like Growth Factor 1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide). |
Buffer/Preservatives | 0.2 mg/ml with 0.1 mg/ml rAlbumin (US sourced), 0.05% sodium azide |
Note | For research use only |
Application notes | Optimal dilution of the antibody should be determined by the researcher. |
Expiration Date | 12 months from date of receipt. |
Flow cytometry testing of human K562 cells with recombinant Insulin-like Growth Factor 1 antibody (clone IGF1/2872R); Red=isotype control, Blue= recombinant Insulin-like Growth Factor 1 antibody.
SDS-PAGE analysis of purified, BSA-free recombinant Insulin-like Growth Factor 1 antibody (clone IGF1/2872R) as confirmation of integrity and purity.
FACS, IF, NeA | |
Human, Mouse, Rat | |
Mouse | |
Monoclonal | |
Unconjugated |
IHC-P | |
Human | |
Mouse | |
Monoclonal | |
Unconjugated |
FACS, IF, NeA | |
Human, Mouse, Rat | |
Mouse | |
Monoclonal | |
Unconjugated |
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