iFSP1

• Catalog Number: orb1309551
• Category: Small Molecules
• Description: iFSP1
• CAS Number: 150651-39-1
• Purity: 99.74%
• MW: 323.35
• SMILES: C(#N)C=1C=2N(C=3C(N2)=CC=CC3)C(N)=C(C#N)C1C4=CC=C(C)C=C4
• Formula: C₂₀H₁₃N₅
• Biological Activity: iFSP1, a potent, selective, and glutathione-independent ferroptosis suppressor protein 1 (FSP1) (AIFM2) inhibitor with an EC50 of 103 nM, sensitizes diverse human cancer cell lines to ferroptosis inducers like (1S,3R)-RSL3. It uniquely triggers ferroptosis in GPX4-knockout cells overexpressing FSP1.
• Storage: Store at -20°C for 12 months.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.