iFSP1

• Catalog Number: orb1309551
• Category: Small Molecules
• Description: iFSP1
• CAS Number: 150651-39-1
• Purity: 99.74%
• MW: 323.35
• SMILES: Cc1ccc(cc1)-c1c(C#N)c(N)n2c3ccccc3nc2c1C#N
• Formula: C₂₀H₁₃N₅
• Biological Activity: iFSP1, a potent, selective, and glutathione-independent ferroptosis suppressor protein 1 (FSP1) (AIFM2) inhibitor with an EC50 of 103 nM, sensitizes diverse human cancer cell lines to ferroptosis inducers like (1S,3R)-RSL3. It uniquely triggers ferroptosis in GPX4-knockout cells overexpressing FSP1.
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.