IFNAR1 Recombinant Antibody [1B12]

• Catalog Number: orb1995821
• Category: Antibodies
• Description: IFNAR1 Recombinant Antibody [1B12]
• Clonality: Recombinant
• Tested applications: ELISA
• Immunogen: A synthesized peptide derived from human IFNAR1
• Form/Appearance: Liquid
• Conjugation: Unconjugated
• Storage: -20°C or -80°C
• Buffer/Preservatives: Liquid
• Alternative names: alpha-type antiviral protein;AVP;beta-type antivir
• Note: For research use only
• Application notes: Dilution Info: Component of the receptor for type I interferons, including interferons alpha, IFNB1 and IFNW1 (PubMed:2153461, PubMed:7665574, PubMed:10049744, PubMed:14532120, PubMed:15337770, PubMed:21854986). Functions in general as heterodimer with IFNAR2 (PubMed:7665574, PubMed:10049744, PubMed:21854986). Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta-subunits themselves (PubMed:7665574, PubMed:21854986). Can form an active IFNB1 receptor by itself and activate a signaling cascade that does not involve activation of the JAK-STAT pathway (By similarity).
• Expiration Date: 12 months from date of receipt.