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Catalog Number | orb1910728 |
---|---|
Category | Small Molecules |
Description | icFSP1 is a compound class of 3-phenylquinazolinones. icFSP1, unlike iFSP1, is the first described on-target FSP1 inhibitor, does not competitively inhibit FSP1 enzyme activity, but instead triggers subcellular relocalization of FSP1 from the membrane and FSP1 condensation before ferroptosis induction, in synergism with GPX4 inhibition. |
CAS Number | [1115910-36-5] |
MW | 459.5 |
SMILES | CC1=NC2=CC=CC=C2C(=O)N1C3=CC=C(C=C3)NC(=O)CC4=CC(=C(C(=C4)OC)OC)OC |
Formula | C26H25N3O5 |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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