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ICCB-19 hydrochloride
Catalog Number: orb1298514
| Catalog Number | orb1298514 |
|---|---|
| Category | Small Molecules |
| Description | ICCB-19 hydrochloride |
| CAS Number | 1803605-68-6 |
| Purity | 99.30% |
| MW | 291.84 |
| SMILES | Cl.O=C(CSC1=NCCN1)NC1CCCCCC1 |
| Formula | C12H22ClN3OS |
| Biological Activity | ICCB-19 hydrochloride (ICCB-19 HCl) is an inhibitor of TRADD (TNFRSF1A Associated Via Death Domain). It binds to a pocket on the N-terminal TRAF2-binding domain of TRADD (TRADD-N), which interacts with the C-terminal domain (TRADD-C) and TRAF2 to modulate the ubiquitination of RIPK1 and beclin 1. |
| Storage | -20°C |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
