IACS-010759 hydrochloride

• Catalog Number: orb1700376
• Category: Small Molecules
• Description: IACS-010759 hydrochloride
• CAS Number: 1807523-99-4
• Purity: 98.00%
• MW: 599.03
• SMILES: Cl.Cc1nc(nn1Cc1cccc(c1)N1CCC(CC1)S(C)(=O)=O)-c1nc(no1)-c1ccc(OC(F)(F)F)cc1
• Formula: C₂₅H₂₆ClF₃N₆O₄S
• Biological Activity: IACS-010759 is a potent inhibitor of complex I of OXPHOS with orally bioavailable. IACS-10759 effectively inhibits ATP production and oxygen consumption in isolated mitochondria, and inhibits the conversion of NADH to NAD+ in immunoprecipitated complex I in low nM range. IACS-10759 shows significant efficacy in multiple tumor indications both in vitro and in vivo.
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.