I194496

• Catalog Number: orb2695455
• Category: Small Molecules
• Description: I194496 is an effective inhibitor of cystathionine γ-lyase (CSE) with an IC50 value of 0.79 mM. It inhibits the growth of human TNBC cells by dual targeting the PI3K/Akt and Ras/Raf/ERK pathways. Additionally, I194496 suppresses the metastasis of human TNBC cells by downregulating the Anxa2/STAT3 and VEGF/FAK/Paxillin signaling pathways.
• CAS Number: 445238-07-3
• MW: 579.58
• SMILES: O=C(NC1=CC=C(C=C1)S(=O)(=O)NC=2C=CC=CC2OC)C=3C=NN4C3N=C(C=C4C(F)F)C=5C=CC(OC)=CC5
• Formula: C₂₈H₂₃F₂N₅O₅S
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.