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Catalog Number | orb1308221 |
---|---|
Category | Small Molecules |
Description | Hycanthone |
CAS Number | 3105-97-3 |
Purity | 98.78% |
MW | 356.48 |
SMILES | C(O)C1=C2C(=C(NCCN(CC)CC)C=C1)C(=O)C=3C(S2)=CC=CC3 |
Formula | C20H24N2O2S |
Biological Activity | Hycanthone (Etrenol(mesylate)) is a potent drug of antischistosomal. Hycanthone is a DNA intercalator that inhibits RNA synthesis and DNA topoisomerases I and II. Hycanthone inhibits nucleic acid biosynthesis and inhibits APE1 via direct protein binding(KD: 10 nM). |
Storage | Store at -20°C for 12 months. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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