Human PLAU / uPA Protein(activated by trypsin)

• Catalog Number: orb613660
• Category: Proteins
• Description: Human PLAU, His Tag (activated by trypsin) is expressed from human 293 cells (HEK293). It contains AA Ser 21 - Leu 431 (Accession # P00749-1).
• Reactivity: Human
• Tag: C-6×His
• Form/Appearance: Powder
• Purity: 90%
• Conjugation: Unconjugated
• MW: 15.3 kDa, 17.8 kDa and 29.2 kDa
• Target: PLAU
• UniProt ID: P00749
• Protein Sequence: NP_002649.1
• Source: Human PLAU, His Tag (activated by trypsin) (orb613660) is expressed from human 293 cells (HEK293). It contains AA Ser 21 - Leu 431 (Accession # P00749-1).
• Expression System: HEK293
• Biological Origin: Human
• Expression Region: Ser 21 - Leu 431
• Endotoxins: 1.0 EU per μg
• NCBI: NP_002649.1
• Storage: -20℃
• Buffer/Preservatives: 25 mM HEPES, 150 mM NaCl, pH7.5
• Alternative names: Urokinase,PLAU,ATF,UPA,URK,u-PA,BDPLT5,QPD
• Note: For research use only
• Application notes: This protein carries a polyhistidine tag at the C-terminus. The active form of Human PLAU is a disulfide-linked heterodimer composed of long chain A (Ser 21 - Phe 177) and chain B (Ile 179 - Leu 431) with calculated MW of 17.8 kDa and 29.2 kDa. The long chain A is further cleaved to yield a short chain A (Lys 156 - Phe 177) and N-terminal fragment (Ser 21 - Lys 155) with calculated MW of 15.3 kDa. The protein migrates as 17 kDa (N-terminal fragment), 32-35 kDa (chain B) and 45-50 kDa (long chain A & chain B) under non-reducing (NR) condition (SDS-PAGE) due to glycosylation.
• Expiration Date: 6 months from date of receipt.