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Human PCSK9 Protein

Catalog Number: orb257737

Catalog Number	orb257737
Category	Proteins
Description	Human PCSK9, His Tag is expressed from human 293 cells (HEK293). It contains AA Gln 31 - Gln 692 (Accession # Q8NBP7-1).
Reactivity	Human
Tag	C-10×His
Form/Appearance	Powder
Purity	90%
Conjugation	Unconjugated
MW	13.8 kDa and 59.2 kDa
Target	PCSK9
UniProt ID	Q8NBP7
Protein Sequence	AAI66619.1
Source	Human PCSK9, His Tag (orb257737) is expressed from human 293 cells (HEK293). It contains AA Gln 31 - Gln 692 (Accession # Q8NBP7-1).
Expression System	HEK293
Biological Origin	Human
Expression Region	Gln 31 - Gln 692
Endotoxins	1.0 EU per μg
NCBI	AAI66619.1
Storage	-20℃
Buffer/Preservatives	PBS, pH7.4
Alternative names	PCSK9,FH3,HCHOLA3,LDLCQ1,NARC1,PC9 Read more...
Note	For research use only
Application notes	This protein carries a polyhistidine tag at the C-terminus. This protein undergoes autocatalytic cleavage to release the pro-peptide and mature chain. The pro-peptide and mature chain are associated through non‑covalent interactions and with a calculated MW of 13.8 kDa and 59.2 kDa respectively. The protein migrates as 17 kDa and 65-70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Expiration Date	6 months from date of receipt.

SDS-PAGE analysis of Human PCSK9 protein

Line graph illustrates about the sensitivity range of Human PCSK9 protein using different concentrations

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Conjugation:	Unconjugated
Purity:	90%
MW:	13.8 kDa and 58.2 kDa
Source:	Human PCSK9 (D374Y), His Tag (orb257745) is expressed from human 293 cells (HEK293). It contains AA Gln 31 - Gln 692 (Accession # Q8NBP7-1 (D374Y)).

Sizes Available: 1 mg, 50 μg

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Conjugation:	Unconjugated
Purity:	95%
MW:	13.9 kDa and 59.4 kDa
Source:	Rhesus macaque PCSK9, His Tag (orb257736) is expressed from human 293 cells (HEK293). It contains AA Gln 31 - Gln 692 (Accession # A8T666).

Sizes Available: 1 mg, 50 μg

Conjugation:	Unconjugated
Purity:	The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
MW:	The protein has a predicted molecular mass of 97.2 kDa after removal of the signal peptide.The apparent molecular mass of PCSK9-hFc is approximately 100-130 kDa due to glycosylation.
Source:	Mammalian

Sizes Available: 100 μg, 10 μg, 50 μg