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Catalog Number | orb1496186 |
---|---|
Category | Proteins |
Description | Oncostatin-M-specific receptor subunit beta(OSMRB) alos know as Interleukin-31 receptor subunit beta (IL-31RB), is an alternative subunit (OSMRβ) for an OSM receptor complex (a heterodimer of gp130 and OSMRβ), that is activated by OSM but not by LIF. OSMR beta associates with the low affinity OSM·gp130 complex to form a high affinity heterodimeric receptor that is capable of transducing OSM-specific signaling events. |
Reactivity | Human |
Tag | C-10×His |
Form/Appearance | Powder |
Purity | 95% |
Conjugation | Unconjugated |
MW | 83.0 kDa |
Target | OSMR |
UniProt ID | Q99650 |
Source | Human OSMR, His Tag (orb1496186) is expressed from human 293 cells (HEK293). It contains AA Glu 28 - Met 740 (Accession # Q99650-1). |
Expression System | HEK293 |
Biological Origin | Human |
Expression Region | Glu 28 - Met 740 |
Endotoxins | 1.0 EU per μg |
Storage | -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower. |
Buffer/Preservatives | PBS, pH7.4 |
Alternative names | Oncostatin-M-specific receptor subunit beta,Interl Read more... |
Note | For research use only |
Application notes | This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 83.0 kDa. The protein migrates as 105-125 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Expiration Date | 6 months from date of receipt. |
Unconjugated | |
95% | |
82.8 kDa | |
Cynomolgus OSMR, His Tag (orb1496200) is expressed from human 293 cells (HEK293). It contains AA Glu 28 - Ser 737 (Accession # A0A2K5UFW5-1). |
The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining. | |
The protein has a predicted molecular mass of 81.9 kDa after removal of the signal peptide. The apparent molecular mass of OSMR-His is approximately 100-250 kDa due to glycosylation. | |
Mammalian |
Greater than 85% as determined by SDS-PAGE. | |
31.3 kDa | |
E.coli |
ELISA, MS, SDS-PAGE, WB | |
Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. | |
Human cells |
≥90% as determined by SDS-PAGE | |
This protein contains the human OSMRB(Glu28-Ser739) was fused with the C-terminal His Tag and expressed in E. coli. |