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Human IL2 protein
Catalog Number: orb594825
| Catalog Number | orb594825 |
|---|---|
| Category | Proteins |
| Description | Recombinant Human Interleukin-2(IL2),Partial (Active) |
| Tag | C-terminal 6xHis-tagged |
| Form/Appearance | Lyophilized powder |
| Purity | Greater than 95% as determined by SDS-PAGE. |
| MW | 16.5 kDa |
| UniProt ID | P60568 |
| Protein Sequence | APTSSSTKKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPKKATELKHLQCLEEELKPLEEVLNLAQSKNFHFDPRDVVSNINVFVLELKGSETTFMCEYADETATIVEFLNRWITFCQSIISTLT |
| Protein Length | Full Length of Mature Protein |
| Source | Mammalian cell |
| Biological Origin | Homo sapiens (Human) |
| Biological Activity | The ED50 as determined in a cell proliferation assay using CTLL‑2 mouse cytotoxic T cells is 151.39 pg/ml. |
| Expression Region | 21-153aa(L80F & R81D & L85V & I86V & I92F) |
| Endotoxins | Less than 1.0 EU/µg as determined by LAL method. |
| Storage | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃. |
| Buffer/Preservatives | Lyophilized from a 0.2 μm filtered 1xPBS, pH 7.4 |
| Alternative names | Interleukin-2; IL-2; T-Cell Growth Factor; TCGF; A Read more... |
| Background | Interleukin-2(IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system，belongs to the IL-2 family. It is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions that are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine-activated killer cells, monocytes, macrophages and oligodendrocytes. New research has shown that IL-2 mutant reduced toxicity while being more potent at stimulating anti-tumor effector immune cell |
| Note | For research use only |
| Application notes | Partial |
| Expiration Date | 6 months from date of receipt. |
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
- Item 1 of 1
Human IL2 protein [orb594792]
Greater than 95% as determined by SDS-PAGE.
15.5 kDa
E.coli
1 mg, 500 μg, 10 μg, 50 μg - Item 1 of 1
Human IL2 protein [orb594804]
Greater than 95% as determined by SDS-PAGE.
16.4 kDa
Mammalian cell
500 μg, 1 mg, 10 μg, 50 μg - Item 1 of 1
Human IL2 protein (Active) [orb358968]
> 97% as determined by SDS-PAGE and HPLC.
15.4 kDa
E.Coli
10 μg, 100 μg, 500 μg - Item 1 of 2
Human IL-2 R alpha Protein, His Tag [orb257613]
Unconjugated
95%
23.6 kDa
Human IL-2 R alpha, His Tag (orb257613) is expressed from human 293 cells (HEK293). It contains AA Glu 22 - Cys 213 (Accession # NP_000408).
1 mg, 100 μg - Item 1 of 2
Human IL-2 R alpha Protein, Fc Tag [orb257608]
Unconjugated
95%
48.4 kDa
Human IL-2 R alpha Protein, Fc Tag (orb257608) is expressed from human 293 cells (HEK293). It contains AA Glu 22 - Cys 213 (Accession # NP_000408).
1 mg, 100 μg
