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Catalog Number | orb570285 |
---|---|
Category | Proteins |
Description | Human IL-6 R alpha, Fc Tag is expressed from human 293 cells (HEK293). It contains AA Leu 20 - Pro 365 (Accession # P08887-1). |
Reactivity | Human |
Tag | C-Fc |
Form/Appearance | Powder |
Purity | 95% |
Conjugation | Unconjugated |
MW | 65.0 kDa |
Target | IL-6 R alpha |
UniProt ID | P08887 |
Source | Human IL-6 R alpha, Fc Tag (orb570285) is expressed from human 293 cells (HEK293). It contains AA Leu 20 - Pro 365 (Accession # P08887-1). |
Expression System | HEK293 |
Biological Origin | Human |
Biological Activity | Loaded Human IL-6 R alpha, Fc Tag on Protein A Biosensor, can bind Human IL-6, premium grade with an affinity constant of 35.9 nM as determined in BLI assay (ForteBio Octet Red96e) (Routinely tested). |
Expression Region | Leu 20 - Pro 365 |
Endotoxins | 1.0 EU per μg |
NCBI | NP_000556.1 |
Storage | -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower. |
Buffer/Preservatives | Tris with Glycine, Arginine and NaCl, pH7.5 |
Alternative names | IL6R,CD126,IL-6R-1,IL-6RA,IL6RA,IL-6R-alpha,IL6RQ, Read more... |
Note | For research use only |
Application notes | This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 65.0 kDa. The protein migrates as 70-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Expiration Date | 6 months from date of receipt. |
Loaded Human IL-6 R alpha, Fc Tag (Cat. No. orb570285) on Protein A Biosensor, can bind Human IL-6, premium grade (Cat. No. orb257601) with an affinity constant of 35.9 nM as determined in BLI assay (ForteBio Octet Red96e) (Routinely tested).
Unconjugated | |
95% | |
39.4 kDa | |
Human IL-6 R alpha, His Tag (orb257625) is expressed from human 293 cells (HEK293). It contains AA Leu 20 - Pro 365 (Accession # NP_000556.1). |