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Catalog Number | orb1818948 |
---|---|
Category | Proteins |
Description | Fibroblast growth factor-5 (FGF5) is a member of the fibroblast growth factor (FGF) family and acts as a crucial regulator of hair growth and an oncogenic factor in several human cancers. Generally, Fibroblast growth factor 5 (FGF5) is widely expressed in embryonic but scarcely in adult tissues. Overexpression of FGF5 has been associated with prostate cancer, pancreatic cancer, breast cancer, renal cell carcinoma, etc |
Reactivity | Human |
Tag | His Tag |
Form/Appearance | Powder |
Purity | > 90% as determined by SDS-PAGE |
Conjugation | Unconjugated |
MW | 29.4 kDa |
Target | FGF-5 |
UniProt ID | P12034 |
Source | Human FGF-5 Protein, His Tag (orb1818948) is expressed from E. coli cells. It contains AA Glu 23 - Gly 268 (Accession # P12034-1). |
Expression System | E. coli |
Biological Activity | Human FGF-5 Protein, His Tag captured on CM5 chip via anti-His antibody can bind Human FGF R2, Fc Tag with an affinity constant of 63.3 nM as determined in a SPR assay |
Expression Region | AA Glu 23 - Gly 268 |
Endotoxins | Less than 1.0 EU per μg by the LAL method |
Storage | For long term storage, the product should be stored at lyophilized state at -20°C or lower |
Buffer/Preservatives | Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant |
Alternative names | FGF-5, Fibroblast growth factor 5, HBGF-5 Read more... |
Note | For research use only |
Application notes | This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 29.4 kDa. The protein migrates as 35-38 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE). |
Expiration Date | 6 months from date of receipt. |
Human FGF-5 Protein, His Tag captured on CM5 chip via anti-His antibody can bind Human FGF R2, Fc Tag with an affinity constant of 63.3 nM as determined in a SPR assay.
Human FGF-5 Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90%
98.00% | |
62.4 kDa (predicted) |