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Human CXCL1 Protein, Fc Tag
Catalog Number: orb1496298
| Catalog Number | orb1496298 |
|---|---|
| Category | Proteins |
| Description | Chemokine (C-X-C motif) ligand 1 (CXCL1) is a small molecule of cytokines belonging to the CXC chemokine family. Also known as growth-regulated oncogene alpha (Growth-regulated oncogene alpha, GROα). It's also known as keratinocytes-derived chemokine (KC) in mice or cytokine-induced neutrophil chemoattractant type-1 (CINC-1) in rats. In humans, this protein is encoded by the gene Cxcl1 and is located on human chromosome 4 among genes for other CXC chemokines. The chemokine CXCL1 is expressed by macrophages, neutrophils and epithelial cells. The chemokine CXCL1 has a chemotactic effect on neutrophils. CXCL1 binds to the chemokine receptor CXCR2 and plays a role in cell chemotaxis. Human CXCL1 is clustered on chromosome 4 adjacent to many CXC chemokine genes. Major roles of CXCL1 include neovascularization, inflammation, wound healing, and tumorigenesis. |
| Reactivity | Human |
| Tag | C-Fc |
| Form/Appearance | Powder |
| Purity | 95% |
| Conjugation | Unconjugated |
| MW | 34.3 kDa |
| Target | CXCL1 |
| UniProt ID | P09341 |
| Source | Human CXCL1, Fc Tag (orb1496298) is expressed from human 293 cells (HEK293). It contains AA Ala 35 - Asn 107 (Accession # P09341). |
| Expression System | HEK293 |
| Biological Origin | Human |
| Expression Region | Ala 35 - Asn 107 |
| Endotoxins | 1.0 EU per μg |
| Storage | -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower. |
| Buffer/Preservatives | PBS, pH7.4 |
| Alternative names | Growth-regulated alpha protein, C-X-C motif chemok Read more... |
| Note | For research use only |
| Application notes | This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 34.3 kDa. The protein migrates as 37-43 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
| Expiration Date | 6 months from date of receipt. |
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Human CXCL1 Protein, hFc Tag [orb1291046]
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
The protein has a predicted molecular mass of 34.0 kDa after removal of the signal peptide.The apparent molecular mass of hFc-CXCL1 is approximately 35-40 kDa due to glycosylation.
Mammalian
100 μg, 10 μg, 50 μg
