Human BACE-1 Protein

• Catalog Number: orb257210
• Category: Proteins
• Description: Human BACE-1, Tag Free is expressed from human 293 cells (HEK293). It contains AA Thr 22 - Thr 457 (Accession # NP_036236.1).
• Reactivity: Human
• Tag: Native
• Form/Appearance: Powder
• Purity: 98%
• Conjugation: Unconjugated
• MW: 49.0 kDa
• Target: BACE-1
• UniProt ID: P56817
• Protein Sequence: NP_036236.1
• Source: Human BACE-1, Tag Free (orb257210) is expressed from human 293 cells (HEK293). It contains AA Thr 22 - Thr 457 (Accession # NP_036236.1).
• Expression System: HEK293
• Biological Origin: Human
• Expression Region: Thr 22 - Thr 457
• Endotoxins: 1.0 EU per μg
• NCBI: NP_036236.1
• Storage: -20℃
• Buffer/Preservatives: 50 mM Tris, pH8.0
• Alternative names: BACE1,ASP2,BACE,FLJ90568,HSPC104,KIAA1149,Memapsin
• Note: For research use only
• Application notes: This protein carries no "tag". The protein has a calculated MW of 49.0 kDa. The protein migrates as 53-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Expiration Date: 6 months from date of receipt.

References

Peters-Libeu, Clare et al. sAβPPα is a Potent Endogenous Inhibitor of BACE1 J Alzheimers Dis, 47, 545-555 (2015)

PubMed: 26401691

SDS-PAGE analysis of Human BACE-1 protein