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HQL-79

HQL-79

Catalog Number: orb1707205

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Catalog Numberorb1707205
CategorySmall Molecules
DescriptionHQL-79
CAS Number162641-16-9
Purity98%
MW377.48
SMILESC(CN1CCC(CC1)OC(c1ccccc1)c1ccccc1)Cc1nnn[nH]1
FormulaC22H27N5O
Biological ActivityHQL-79 is a selective and orally active human hematopoietic prostaglandin D synthase (H-PGDS) inhibitor. It inhibits the synthesis of PGD2 and acts as an anti-allergic agent (Kd: 0.8 μM and IC50: 6 μM). It also shows no obvious effect on COX-1, COX-2, m-PGES, or L-PGDS.
Storage-20°C
NoteFor research use only
Expiration Date12 months from date of receipt.
  • HQL-79 [orb573072]

    [162641-16-9]

    377.48

    C22H27N5O

    250 mg, 100 mg, 1 g