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Catalog Number | orb1707205 |
---|---|
Category | Small Molecules |
Description | HQL-79 |
CAS Number | 162641-16-9 |
Purity | 98% |
MW | 377.48 |
SMILES | C(CN1CCC(CC1)OC(c1ccccc1)c1ccccc1)Cc1nnn[nH]1 |
Formula | C22H27N5O |
Biological Activity | HQL-79 is a selective and orally active human hematopoietic prostaglandin D synthase (H-PGDS) inhibitor. It inhibits the synthesis of PGD2 and acts as an anti-allergic agent (Kd: 0.8 μM and IC50: 6 μM). It also shows no obvious effect on COX-1, COX-2, m-PGES, or L-PGDS. |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |