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Catalog Number | orb1306101 |
---|---|
Category | Small Molecules |
Description | HPI 1 |
CAS Number | 599150-20-6 |
Purity | 94.40% |
MW | 463.52 |
SMILES | COCCOC(=O)C1=C(C)NC2=C(C1C1=CC(O)=CC=C1)C(=O)CC(C2)C1=C(OC)C=CC=C1 |
Formula | C27H29NO6 |
Biological Activity | HPI 1 is a hedgehog (Hh) signaling inhibitor. Inhibits Sonic hedgehog (Shh)-, SAG- and Gli-induced Hh pathway activation in Shh-LIGHT2 cells (IC50 values are 1.5, 1.5, 4, and 6 μM for Shh-, SAG-, Gli2- and Gli1-induced activation). |
Storage | Store at -20°C for 12 months. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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