HKI 357

• Catalog Number: orb525692
• Category: Small Molecules
• Description: HKI 357 is an irreversible dual inhibitor of the EGF receptor tyrosine kinases EGFR and HER2 (IC50s = 34 and 33 nM, respectively).
• CAS Number: [848133-17-5]
• MW: 574.1
• SMILES: O=C(/C=C/CN(C)C)N([H])C1=C(OCC)C=C(N=CC(C#N)=C2N([H])C3=CC=C(OCC4=CC=CC(F)=C4)C(Cl)=C3)C2=C1
• Formula: C₃₁H₂₉ClFN₅O₃
• Note: For research use only
• Expiration Date: 12 months from date of receipt.