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HIV-1 protease-IN-4
Catalog Number: orb1982893
| Catalog Number | orb1982893 |
|---|---|
| Category | Small Molecules |
| Description | HIV-1 protease-IN-4 (Compound II-22), a potent inhibitor of the HIV-1 protease, acts as a prodrug for atazanavir and significantly enhances its bioavailability in rat plasma, achieving a 5-fold increase in the area under the curve (AUC) and a 67-fold increase in concentration at 24 hours (C24) compared to oral administration of atazanavir alone [1]. |
| Purity | 98.00% |
| MW | 920.1 |
| Formula | C48H69N7O11 |
| Biological Activity | HIV-1 protease-IN-4 (Compound II-22), a potent inhibitor of the HIV-1 protease, acts as a prodrug for atazanavir. It notably enhances the bioavailability of atazanavir in rat plasma, achieving a 5-fold increase in the area under the curve (AUC) and a 67-fold increase in concentration at 24 hours (C24) compared to oral administration of atazanavir alone [1]. |
| Storage | -20°C |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
