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HIV-1 inhibitor-57
Catalog Number: orb1944458
| Catalog Number | orb1944458 |
|---|---|
| Category | Small Molecules |
| Description | HIV-1 Inhibitor-57 (Compound 12g) is an antiviral agent that potently inhibits both wild-type and five common NNRTI-resistant strains of HIV-1, exhibiting EC50 values between 0.024 and 0.0010 μM. It achieves this efficacy by forming supplementary interactions with residues surrounding the binding site in the HIV-1 reverse transcriptase (RT) [1]. |
| CAS Number | 2745197-24-2 |
| Purity | 98.00% |
| MW | 493.55 |
| SMILES | FC1=C(C=CC(NC=2N=C(OC3=C(C)C=C(/C=C/C#N)C=C3C)C=CN2)=C1)N4CCS(=O)(=O)CC4 |
| Formula | C25H24FN5O3S |
| Biological Activity | HIV-1 Inhibitor-57 (Compound 12g) is an antiviral agent that potently inhibits both wild-type and five common NNRTI-resistant strains of HIV-1, exhibiting EC50 values between 0.024 and 0.0010 μM. It achieves this efficacy by forming supplementary interactions with residues surrounding the binding site in the HIV-1 reverse transcriptase (RT) [1]. |
| Storage | -20°C |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
