Hemagglutinin 5 Antibody

• Catalog Number: orb1821654
• Category: Antibodies
• Description: Hemagglutinin 5 Antibody
• Species/Host: Human
• Clonality: Monoclonal
• Clone Number: H5.3
• Tested applications: NeA
• Reactivity: Virus
• Isotype: IgG1
• Immunogen: H5.3 was generated from hybridomas created by fusing PBMCs (peripheral blood mononuclear cells) from human donors who had been previously received an A/Vietnam/1203/2004 H5N1 subunit vaccine with myeloma cells. The hybridoma cells were screened for those showing binding affinity for H5 HA.
• Concentration: 1 mg/ml
• Conjugation: Unconjugated
• Target: Hemagglutinin 5
• UniProt ID: Q5EP31
• Storage: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
• Buffer/Preservatives: PBS with 0.02% Proclin 300.
• Alternative names: H5 HA
• Note: For research use only
• Application notes: H5.3 binds to H5 where it is able to block the receptor binding site on HA by inserting its CDR3 into the site (IC50 ~ 20 ng/ml). H5.3 can neutralize wild-type VN/1203, rdt VN/1203 K and VN/1203 F pseudovirions, all with IC50s of 5 ng/ml. This antibody also has potent HI (hemagglutination inhibition) activity (80 ng/ml).
• Expiration Date: 12 months from date of receipt.