You have no items in your shopping cart.
You have no items in your shopping cart.
Catalog Number | orb1821653 |
---|---|
Category | Antibodies |
Description | Hemagglutinin 5 Antibody |
Species/Host | Human |
Clonality | Monoclonal |
Clone Number | H5.3 |
Tested applications | NeA |
Reactivity | Virus |
Isotype | IgG |
Immunogen | H5.3 was generated from hybridomas created by fusing PBMCs (peripheral blood mononuclear cells) from human donors who had been previously received an A/Vietnam/1203/2004 H5N1 subunit vaccine with myeloma cells. The hybridoma cells were screened for those showing binding affinity for H5 HA. |
Concentration | 1 mg/ml |
Conjugation | Unconjugated |
Target | Hemagglutinin 5 |
UniProt ID | Q5EP31 |
Storage | Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C. |
Buffer/Preservatives | PBS with 0.02% Proclin 300. |
Alternative names | H5 HA Read more... |
Note | For research use only |
Application notes | H5.3 binds to H5 where it is able to block the receptor binding site on HA by inserting its CDR3 into the site (IC50 ~ 20 ng/ml). H5.3 can neutralize wild-type VN/1203, rdt VN/1203 K and VN/1203 F pseudovirions, all with IC50s of 5 ng/ml. This antibody also has potent HI (hemagglutination inhibition) activity (80 ng/ml). |
Expiration Date | 12 months from date of receipt. |
Filter by Rating