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HEI3090

HEI3090

Catalog Number: orb2663683

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Catalog Numberorb2663683
CategorySmall Molecules
DescriptionHEI3090 is an activator of the P2X7R receptor. This compound enhances the production of IL-18 by stimulating dendritic cells that express P2X7R, which in turn promotes the production of IFN-γ by natural killer cells and CD4T cells within tumors, triggering a sustained anti-tumor response. Additionally, HEI3090 can be used to improve the efficacy of αPD-1 therapy in non-small cell lung cancer (NSCLC).
CAS Number2377167-56-9
Purity98.00%
MW441.70
SMILESC(NC=1C=CC(Cl)=NC1)(=O)N2[C@H](C(NCC3=C(Cl)C=C(Cl)C=C3)=O)CCC2=O
FormulaC18H15Cl3N4O3
Storage-20°C
NoteFor research use only
Expiration Date12 months from date of receipt.