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Catalog Number | orb2663683 |
---|---|
Category | Small Molecules |
Description | HEI3090 is an activator of the P2X7R receptor. This compound enhances the production of IL-18 by stimulating dendritic cells that express P2X7R, which in turn promotes the production of IFN-γ by natural killer cells and CD4T cells within tumors, triggering a sustained anti-tumor response. Additionally, HEI3090 can be used to improve the efficacy of αPD-1 therapy in non-small cell lung cancer (NSCLC). |
CAS Number | 2377167-56-9 |
Purity | 98.00% |
MW | 441.70 |
SMILES | C(NC=1C=CC(Cl)=NC1)(=O)N2[C@H](C(NCC3=C(Cl)C=C(Cl)C=C3)=O)CCC2=O |
Formula | C18H15Cl3N4O3 |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |