HDAC8 Antibody

• Catalog Number: orb1730430
• Category: Antibodies
• Description: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. May play a role in smooth muscle cell contractility.
• Species/Host: Rabbit
• Clonality: Polyclonal
• Tested applications: FC, IP, WB
• Reactivity: Human, Mouse, Rat
• Isotype: Rabbit IgG
• Immunogen: A synthesized peptide derived from human HDAC8
• Dilution range: IP: 1/20; WB: 1/500-1/1000; RCM: 1/50-1/100
• Conjugation: Unconjugated
• MW: Calculated MW: 42 kDa; Observed MW: 42 kDa
• Entrez: 55869
• UniProt ID: Q9BY41
• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Alternative names: HDAC8; HDACL1; CDA07; Histone deacetylase 8; HD8
• Note: For research use only
• Expiration Date: 12 months from date of receipt.