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Catalog Number | orb1732847 |
---|---|
Category | Antibodies |
Description | Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D. |
Species/Host | Mouse |
Clonality | Monoclonal |
Clone Number | 7C3 |
Tested applications | IP, WB |
Reactivity | Human, Monkey, Mouse, Rat |
Isotype | Mouse IgG2a |
Immunogen | Purified recombinant human HDAC4 protein fragments expressed in E.coli |
Concentration | 1mg/ml |
Dilution range | IP: 1/20; WB: 1/500-1/1000 |
Conjugation | Unconjugated |
MW | Calculated MW: 119 kDa; Observed MW: 140 kDa |
Entrez | 9759 |
UniProt ID | P56524 |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Buffer/Preservatives | Liquid in PBS containing 50% glycerol, 0.5% rAlbumin and 0.02% sodium azide, pH 7.3. |
Alternative names | EC 3.5.1.98; HA6116; HD 4; HD4; HDAC 4; HDAC A; HD Read more... |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
FC, ICC, IF, IHC, WB | |
Human, Mouse, Rat | |
Rabbit | |
Polyclonal | |
Unconjugated |
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