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HDAC3-IN-5

HDAC3-IN-5

Catalog Number: orb2664456

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Catalog Numberorb2664456
CategorySmall Molecules
DescriptionHDAC3-IN-5 (9c) is a selective inhibitor of HDAC3, exhibiting IC50 values of 4.2 nM for HDAC3, 1629 nM for HDAC2, and 298.2 nM for HDAC1. In vitro, it effectively induces apoptosis in MV4-11 cells and reduces the expression of anti-apoptotic proteins. The development of selective HDAC3 inhibitors like HDAC3-IN-5 (9c) could serve as potential lead compounds for reversing Venetoclax resistance.
Purity98.00%
Storage-20°C
NoteFor research use only
Expiration Date12 months from date of receipt.