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Catalog Number | orb2664456 |
---|---|
Category | Small Molecules |
Description | HDAC3-IN-5 (9c) is a selective inhibitor of HDAC3, exhibiting IC50 values of 4.2 nM for HDAC3, 1629 nM for HDAC2, and 298.2 nM for HDAC1. In vitro, it effectively induces apoptosis in MV4-11 cells and reduces the expression of anti-apoptotic proteins. The development of selective HDAC3 inhibitors like HDAC3-IN-5 (9c) could serve as potential lead compounds for reversing Venetoclax resistance. |
Purity | 98.00% |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |