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Catalog Number | orb692097 |
---|---|
Category | Small Molecules |
Description | HCH6-1 is a competitive antagonist of Formyl peptide receptor 1 (FPR1), an emerging therapeutic target for the discovery of drugs to treat neutrophilic inflammatory diseases. HCH6-1 is a selective FPR1 inhibitor and has protective effects against acute lung injury (ALI). HCH6-1 inhibits superoxide anion generation, elastase release, and chemotaxis in human neutrophils activated by fMLF (an FPR1 agonist). |
CAS Number | [1435265-06-7] |
MW | 469.53 |
SMILES | O=C([C@]([H])(C([H])([H])C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12)N([H])C(C1C([H])=C([H])C([H])=C([H])C=1[H])=O)N([H])[C@@]([H])(C(=O)OC([H])([H])[H])C([H])([H])C1C([H])=C([H])C([H])=C([H])C=1[H] |
Formula | C28H27N3O4 |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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