H4 Receptor antagonist 1

SKU: orb1220678

Description

H4 Receptor antagonist 1 is a potent and selective histamine H4 receptor inverse agonist with an IC50 of 19 nM.

Images & Validation

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Key Properties

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CAS Number	848217-00-5
MW	316.78
Purity	>98% (HPLC)
Formula	C₁₆H₁₇ClN₄O
SMILES	CN1CCN(CC1)c1nc(C)nc2c3cc(Cl)ccc3oc12
Target	Histamine Receptor
Solubility	DMSO:10 mg/mL (31.57 mM)

Bioactivity

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In Vivo	H4 Receptor antagonist 1 indicates that metabolic stability in rat microsomes is very low with only 1% parent compound remaining after 10 min incubation. Read more...
In Vitro	H4 Receptor antagonist 1 is a potent and selective histamine H4 receptor inverse agonist, with an IC50 of 19 nM.

Storage & Handling

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Storage	Storage temperature: -20°C. Stability: ≥ 2 years
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Gene Symbol

Histamine Receptor

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