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Catalog Number | orb1298893 |
---|---|
Category | Small Molecules |
Description | GW6471 |
CAS Number | 880635-03-0 |
Purity | 99.55% |
MW | 619.67 |
SMILES | CCC(=O)NC[C@H](Cc1ccc(OCCc2nc(oc2C)-c2ccccc2)cc1)N\C(C)=C/C(=O)c1ccc(cc1)C(F)(F)F |
Formula | C35H36F3N3O4 |
Biological Activity | GW6471 is an antagonist of PPARα with IC50 of 0.24 μ M. GW6471 enhances the binding affinity of the PPAR α ligand-binding domain to the co-repressor proteins SMRT and NCoR. |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |