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Catalog Number | orb1298893 |
---|---|
Category | Small Molecules |
Description | GW6471 |
CAS Number | 880635-03-0 |
Purity | 98.38% |
MW | 619.67 |
SMILES | C(COC1=CC=C(C[C@H](N/C(=C\C(=O)C2=CC=C(C(F)(F)F)C=C2)/C)CNC(CC)=O)C=C1)C=3N=C(OC3C)C4=CC=CC=C4 |
Formula | C35H36F3N3O4 |
Biological Activity | GW6471 is an antagonist of PPARα with IC50 of 0.24 μ M. GW6471 enhances the binding affinity of the PPAR α ligand-binding domain to the co-repressor proteins SMRT and NCoR. |
Storage | Store at -20°C for 12 months. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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