Guanabenz hydrochloride

SKU: orb1306143

Description

Guanabenz hydrochloride

Research Area

Infectious Disease & Virology, Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 23113-43-1
• MW: 267.54
• Purity: 99.59%
• Formula: C₈H₉Cl₃N₄
• SMILES: ClC1=C(C=NNC(N)=N)C(Cl)=CC=C1.[H]Cl
• Target: Parasite,Adrenergic Receptor
• Solubility: DMSO:55 mg/mL (205.58 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (7.48 mM)

Bioactivity

• In Vivo:
  Maximum concentrations of guanabenz hydrochloride in plasma (1.2 to 5.2 ng/ml) reached 2 to 5 hours after administration of capsules containing 16 or 32 mg of 14C-labelled guanabenz hydrochloride. Guanabenz hydrochloride was 90% bound to human plasma proteins. Guanabenz hydrochloride competed for imidazoline I2-binding sites in brown adipose tissue with Ki of 97 nM.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Adrenergic Receptor, AdrenergicReceptor, antiparasitic, antihypertensive, Beta Receptor, Guanabenz hydrochloride, Guanabenz Hydrochloride, Guanabenz, Inhibitor, high blood pressure, inhibit, NE56490, NE-56490, NE 56490, Parasite, α2-adrenoceptor

Compound Identifiers

PubChem CID

146737