GSK215

• Catalog Number: orb1685568
• Category: Small Molecules
• Description: GSK215
• CAS Number: 2743427-26-9
• Purity: 99.30%
• MW: 985.13
• SMILES: CNC(=O)c1ccccc1Nc1cc(Nc2ccc(cc2OC)N2CCN(CC(=O)N[C@H](C(=O)N3C[C@H](O)C[C@H]3C(=O)N[C@@H](C)c3ccc(cc3)-c3scnc3C)C(C)(C)C)CC2)ncc1C(F)(F)F
• Formula: C₅₀H₅₉F₃N₁₀O₆S
• Biological Activity: GSK215 is a potent and selective PROTAC focal adhesion kinase (FAK) degrader (pDC50= 8.4). GSK215 is designed by the FAK inhibitor VS-4718 and a binder for the VHL E3 ligase. GSK215 can induce rapid and prolonged FAK degradation.
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.